In our modern world, our lives are becoming increasingly hectic.  The lifestyle of active women, especially of those living in urban areas, may lead to unexpected skin problems induced by stress and pollution.

Pollutants attack the skin:
Sulfur dioxide, nitrogen dioxide and gases such as carbon oxide attack skin cells and generate free radicals: they are cytotoxic.

Micro-particles cover the skin with a invisible film, that dulls and poisons it.  These micro-particles come from degradation of hydrocarbons, combustion of oil and fuel, as well as from home and industrial dust.

Day after day, our skin is exposed to these attacks.  The consequences are a dull, dry, wrinkled skin, with loss of tonicity and firmness.

By acting on the causes of these signs, it becomes possible to keep skin in an optimal physiological state, with a radiant complexion and a pleasant touch.

Therefore, PURISOFT has been developed, in order to offer, as a dual active ingredient, the essential elements to fight against pollution effects and to purify the skin.

PURISOFT has a dual activity, combining:

-  the capacity of protecting skin cells against aggressions by pollutants,
-  the efficacy in purifying the skin, by faciliting the removal of all micro-particles, coming from the environment that "asphyxiate" the skin.

PURISOFT is a natural and native peptide, of exotic origin.  It is obtained by mild extraction of Moringa seeds, without using any chemical solvent.  It is manufactured by Laboratoires Serobiologiques, France.

Protocal

Conclusion
PURISOFT shows good protective properties on cell against pollutants: mercury and cadmium, comparable or even better than Foetal calf serum, used as reference substance.

Aim
Evaluation of the anti-pollution efficacy of a hydrogel containing 3% PURISOFT on human skin in culture.  The pollution stress is induced by incubation of skin cultures in presence of cigarette smoke.  The marker used to evaluate the pollution stress intensity is HSP 27.

Protocal

Results

Conclusion
After polllution stress by cigarette smoke, the induction of HSP was strongly increased.  The application of a hydrogel containing 3% PURISOFT significantly decreased the induction of HSP 27 due to the presence of cigarette smoke.  PURISOFT has a good anti-pollution stress efficacy.

Aim
To demonstrate the skin purifying property of a lotion containing 1.5% PURISOFT LS9602.  Coal is used as a model of micro-particle pollution to soil skin.

Protocal
The test has been carried out on 10 female volunteers.

The semi-quantitative evaluation is made by 2 experts according to the  videomicroscopic images.
The scale used reflects the particle pollution:
0 = none             1 = very light          2 = light
3 = moderated    4 = important          5 = very important

Results
1. After application of coal/protective affect against pollution


    
The skin area treated with the lotion containing 1.5% PURISOFT LS 9602 is more protected against coal particles in comparison to the skin are treated with the placebo lotion.

2. After rinsing with water / superficial purifying effect

    

After rinsing with water, the coal particles have significantly decreased on the surface of the skin area treated with the lotion containing 1.5% PURISOFT LS 9602 in comparison to the placebo lotion.

3. After stripping / deep purifying effect

    

The in depth purifying effect of the lotion containing 1.5% PURISOFT LS 9602 is significant in comparison to the placebo lotion.

Videomicroscopy of the skin

1. After application of coal / protective effect against pollution.

    

2. After rinsing with water / superficial purifying effect

    

3. After stripping / deep purifying effect

    
 

• the application of a lotion containing 1.5% PURISOFT LS 9602 protects the skin against particle pollution,
• the incorporation of PURISOFT LS 9602 in a lotion makes skin cleansing easier

PURISOFT LS 9602 has a significant purifying effect.